Triptorelin, sold under the brand names Decapeptyl and Gonapeptyl among others, is a medication that acts as an agonist analog of Gonadotropin-releasing hormone, thus reversibly repressing expression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
GnRH is responsible for telling the pituitary gland in the brain to secrete luteinizing hormone (LH) used for testosterone production, or follicle-stimulating hormone (FSH) used for sperm production. Triptorelin tells the hypothalamus to secrete more GnRH, thus telling the pituitary to secrete LH and FSH, which equals more testosterone in males.
It is a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) and a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts.
Molar Mass: 1 311.473 g/mol -1