Pramipexole 1mg x 30ml

Description

Pramipexole

Pramipexole acts as a partial/full agonist at the following receptors:

• D_2S receptor (K_i = 3.9 nM; IA = 130%)
• D_2L receptor (K_i = 2.2 nM; IA = 70%)
• D₃ receptor (K_i = 0.5 nM; IA = 70%)
• D₄ receptor (K_i = 5.1 nM; IA = 42%)

Pramipexole also possesses low/insignificant affinity (500–10,000 nM) for the 5-HT_1A, 5-HT_1B, 5-HT_1D, and α₂-adrenergic receptors. It has negligible affinity (>10,000 nM) for the D₁, D₅, 5-HT₂, α₁-adrenergic, β-adrenergic, H₁, and mACh receptors.

Formula:                   C10H17N3S

Molar Mass:             211.33 G/MOL -1