Hexarelin 5mg

Description

Hexarelin 5mg

Also known as Examorelin (INN) (developmental code names EP-23905, MF-6003), is a potent, synthetic, peptidic, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue. The primary function of hexarelin is to trigger the release of growth hormone from the anterior pituitary gland. Hexarelin follows multiple courses of action to achieve this purpose. Hexarelin mimics the action of a naturally occurring hormone called ghrelin. Ghrelin is mainly synthesized in the stomach, and it travels via the bloodstream to bind with the growth hormone secretagogue receptor (GHS-R1a) located in the hippocampus.This subsequent binding stimulates a wide array of physiological pathways such as the release of growth hormone (GH), protecting cardiomyocytes, regulating body weight, and developing the musculoskeletal system.

Hexarelin also binds with growth hormone secretagogue receptor (GHS-R1a) (3) similar to ghrelin to initiate a phospholipid-dependent protein kinase (PKC) signaling pathway (1). This leads to the amplified release of growth hormone (GH) due to the coordinated action of the hypothalamus as well as the pituitary gland. Hexarelin is also known to limit the release of somatostatin, also sometimes referred to as growth hormone-inhibiting hormone (GHIH). This leads to higher serum levels of growth hormone (GH). The availability of growth hormone secretagogue receptor (GHS-R1a) in the peripheral organs like the heart, bones, adrenal gland, and digestive tract means that hexarelin can also trigger a localized effect. Particularly, the binding of hexarelin with cardiac receptors called CD36 (3) is a growing area of research.

Hexarelin stimulates other endocrine pathways such as ACTH to cause the release of prolactin as well as cortisol. Hexarelin mainly works by releasing growth hormone. It shows the capabilities to increase muscle growth, improve muscle repair. It is a hexapeptide with the amino acid sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH₂ which was derived from GHRP-6.

Formula:                    C47H58N12O6

Molar Mass:              887.059 G/MOL -1

THIS PRODUCT IS INTENDED FOR RESEARCH ONLY. This designation allows the use of research peptides strictly for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product is NOT for human use and can be harmful if ingested. This product is for research/laboratory use only. This product is NOT in a sterile solution and is NOT to be injected. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and should not be misbranded, misused or mislabeled as a drug, food or cosmetic.